{"id":101927,"date":"2024-09-05T08:54:29","date_gmt":"2024-09-05T08:54:29","guid":{"rendered":"https:\/\/accessmedicalsystems.com\/?post_type=product&#038;p=101927"},"modified":"2024-10-21T07:15:30","modified_gmt":"2024-10-21T07:15:30","slug":"matriderm","status":"publish","type":"product","link":"https:\/\/accessmedicalsystems.com\/product\/matriderm\/","title":{"rendered":"MatriDerm\u00ae"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.25.1&#8243; background_color=&#8221;#d3d3d3&#8243; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;&#8221; custom_margin_last_edited=&#8221;on|desktop&#8221; custom_padding=&#8221;50px||50px||true|false&#8221; custom_padding_tablet=&#8221;50px||50px||true|false&#8221; custom_padding_phone=&#8221;15px||15px||true|false&#8221; background_last_edited=&#8221;on|desktop&#8221; use_background_color_gradient_tablet=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; 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_module_preset=&#8221;default&#8221; text_font=&#8221;|300|||||||&#8221; text_font_size=&#8221;25px&#8221; text_line_height=&#8221;1.5em&#8221; custom_padding=&#8221;|50px|||false|false&#8221; custom_padding_tablet=&#8221;|||10px|false|false&#8221; custom_padding_phone=&#8221;|||10px|false|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; text_line_height_tablet=&#8221;1.5em&#8221; text_line_height_phone=&#8221;1.5em&#8221; text_line_height_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: justify;\"><span>MatriDerm\u00ae is a\u00a0<\/span>unique collagen-elastin-template<span>, which serves as a dermal replacement scaffold and can be applied both in a\u00a0<\/span>One- and Multi-Step Procedure<span>.<\/span><\/p>\n<p style=\"text-align: justify;\"><span><\/span><\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"text-align: justify;\">Open porous matrix<\/li>\n<li style=\"text-align: justify;\">No chemical cross-linking<\/li>\n<li style=\"text-align: justify;\">Native collagen fibers<\/li>\n<li style=\"text-align: justify;\">Contains Elastin<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; 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global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Text shows on click&#8221; module_class=&#8221;text-1&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#000000&#8243; text_font_size=&#8221;15px&#8221; custom_margin=&#8221;|50px||50px|false|true&#8221; custom_margin_tablet=&#8221;|||0px|false|false&#8221; custom_margin_phone=&#8221;&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||0px||true|true&#8221; custom_padding_tablet=&#8221;0px|10px|0px|10px|true|true&#8221; custom_padding_phone=&#8221;|15px||15px|true|true&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; custom_css_before=&#8221;content:%22%22;||border-bottom:0px solid #007bfc;||padding:20px 10px;||position:absolute;||top: -25px;||left: -50px;&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"col-12 order-first\" style=\"text-align: justify;\">\n<h2 class=\"section__headline\"><strong>MatriDerm\u00ae Scientific Rationale<\/strong><\/h2>\n<p><strong><\/strong><\/p>\n<p><strong><\/strong><\/p>\n<\/div>\n<div class=\"col-12\" style=\"text-align: justify;\">\n<p>MatriDerm\u00ae is able to<span>\u00a0<\/span><strong>preserve<\/strong><span>\u00a0<\/span>closeness to human dermis,<span>\u00a0<\/span><strong>accelerat<\/strong><strong>e<\/strong><span>\u00a0<\/span>cell invasion, cell elongation and proliferation and<span>\u00a0<\/span><strong>limit<\/strong><span>\u00a0<\/span>myofibroblast formation and contraction. This scientific performance is as a result of our Advanced CryoSafe\u00ae Method which gently preserves the native structure with no chemical crosslinking.<\/p>\n<p><sup>1.<span>\u00a0<\/span><\/sup><sup>Dill V and Moergelin M, Int Wound J 2020;17(3):618-630<br \/>2. B\u00f6hm S et al.; Materials 2017; 10(9), 1086<\/sup><\/p>\n<p>&nbsp;<\/p>\n<p><strong>ACCELERATES<\/strong><\/p>\n<p>In an animal AV-Loop model number of new formed blood vessels were analyzed in wounds treated with either with MatriDerm\u00ae Dermal Matrix or competitor product. MatriDerm Dermal Matrix<span>\u00a0<\/span><strong>accelerates<span>\u00a0<\/span><\/strong>revascularization.<\/p>\n<footer class=\"content-infographic__footnotes\">Schmidt VJ et al., Ann Plast Surg. 2017;79(1):92-100<\/p>\n<p><span style=\"font-size: 15px;\">\u00a0<\/span><\/p>\n<p><strong>LIMITS<\/strong><\/p>\n<p>In vitro analysis of the formation of myofribroblast phenotype by \u03b1-SMA staining. MatriDerm\u00ae Dermal Matrix<span>\u00a0<\/span><strong>limits<span>\u00a0<\/span><\/strong>myofibroblast formation compared to competitor products. Myofibroblast formation is associated with wound contraction. Limited wound contraction is observed with MatriDerm.3,4,5<sup><\/sup><\/p>\n<footer class=\"content-infographic__footnotes\">1. Dill V and Moergelin M, Int Wound J 2020;17(3):618-630.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>2. Kattan WM et al., J Coll Physicians Surg Pak 2017;27:38-43.<\/p>\n<p>3. De Vries H et al., Wound Repair Regen. 1994;2(1):37-47.<\/p>\n<p>4. De Vries HJ et al., Br J Dermatol. 1995;132(5):690-7.<\/p>\n<p>5. Hur GY, Seo DK, Lee JW., Burns. 2014;40(8):1497-503.<\/p>\n<p>*By measurement of \u03b1-SMA positive fibroblasts<\/p>\n<\/footer>\n<\/footer>\n<\/div>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Text shows on click&#8221; module_class=&#8221;text-2&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#000000&#8243; custom_margin=&#8221;|||48px|false|false&#8221; custom_margin_tablet=&#8221;|||0px|false|false&#8221; custom_margin_phone=&#8221;&#8221; custom_margin_last_edited=&#8221;on|tablet&#8221; custom_padding_tablet=&#8221;|10px||10px|false|true&#8221; custom_padding_phone=&#8221;|15px||15px|false|true&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; custom_css_before=&#8221;content:%22%22;||border-bottom:0px solid #007bfc;||padding:20px 10px;||position:absolute;||top: -25px;||left: -50px;&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2 class=\"section__headline\" style=\"text-align: justify;\"><strong>MatriDerm\u00ae Clinical Performance<\/strong><\/h2>\n<p style=\"text-align: justify;\"><strong><\/strong><\/p>\n<p style=\"text-align: justify;\"><strong>Ensures Active Healing<\/strong><\/p>\n<p style=\"text-align: justify;\">In diabetic foot ulcers the combination of MatriDerm with STSG lead to a shorter healing period compared to STSG alone.<\/p>\n<footer class=\"content-infographic__footnotes\">Modified according to Jeon H. et al., ArchPlast Surg2013, 40(4):403-8<\/p>\n<p style=\"text-align: justify;\">\n<p style=\"text-align: justify;\">\n<p style=\"text-align: justify;\">* p=0.010<\/p>\n<p style=\"text-align: justify;\">1. Compared to STSG alone<\/p>\n<p style=\"text-align: justify;\"><strong>Cost Effective<\/strong><\/p>\n<p style=\"text-align: justify;\">In an RCT the total surgical treatment costs of Full-thickness wounds treated with STSG alone or with MatriDerm Dermal Matrix and STSG were analyzed. The costs do not differ significantly.<\/p>\n<footer class=\"content-infographic__footnotes\">Modified according to Hop M. et al., Burns 2013, 40(3):388-96<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Improves Quality of Wound Healing<\/strong><\/p>\n<p>Long term follow-up study of an intra-individual comparison of patients treated with STSG alone and with MatriDerm Dermal Matrix and STSG to analyze different skin parameter after 12 years of treatment. It demonstrate a long lasting effect on scar quality even after 12 years by the use of MatriDerm Dermal Matrix compared to STSG alone.<\/p>\n<footer class=\"content-infographic__footnotes\">Modified according to Bloemen MC et al., Plast Reconstr Surg, 2010, 125(5):1450-9<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>1. Compared to STSG alone<\/p>\n<p>* p&lt;0.05<\/p>\n<\/footer>\n<\/footer>\n<\/footer>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Text shows on click&#8221; module_class=&#8221;text-3&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#000000&#8243; custom_margin=&#8221;|||48px|false|false&#8221; custom_margin_tablet=&#8221;|||0px|false|false&#8221; custom_margin_phone=&#8221;&#8221; custom_margin_last_edited=&#8221;on|tablet&#8221; custom_padding_tablet=&#8221;|10px||10px|false|true&#8221; custom_padding_phone=&#8221;|15px||15px|false|true&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; custom_css_before=&#8221;content:%22%22;||border-bottom:0px solid #007bfc;||padding:20px 10px;||position:absolute;||top: -25px;||left: -50px;&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2 style=\"text-align: left;\"><strong>MatriDerm\u00ae Indications<\/strong><\/h2>\n<p>&nbsp;<\/p>\n<div class=\"container-fluid px-lg-5\">\n<div class=\"row mx-lg-n5\">\n<div class=\"col-sm-12 col-md-3 px-lg-5\">\n<ul>\n<li>Burns \/ Reconstructive<\/li>\n<li>Burns \/ Acute<\/li>\n<li>Trauma and Acute Wounds<\/li>\n<li>Chronic Wounds<\/li>\n<li>Cancer Excision<\/li>\n<li>Adhesion Barrier<\/li>\n<li>Donor Sites<\/li>\n<li>Mucosal Defects<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=&#8221;on|phone&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221; width_tablet=&#8221;92%&#8221; width_phone=&#8221;94%&#8221; width_last_edited=&#8221;on|phone&#8221; custom_padding_tablet=&#8221;|10px||10px|false|true&#8221; custom_padding_phone=&#8221;|10px||10px|false|true&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_wc_related_products show_price=&#8221;off&#8221; show_rating=&#8221;off&#8221; show_sale_badge=&#8221;off&#8221; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|25px||25px|false|true&#8221; custom_padding_tablet=&#8221;|25px||25px|false|true&#8221; custom_padding_phone=&#8221;|25px||25px|false|true&#8221; custom_padding_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_wc_related_products][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Flexible\u00a0solutions for\u00a0complex\u00a0wound reconstructionMatriDerm\u00ae is a\u00a0unique collagen-elastin-template, which serves as a dermal replacement scaffold and can be applied both in a\u00a0One- and Multi-Step Procedure. 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